BenchArt™ Multi-Blade Tissue Chopper For Tissue Dissociation

$64.00 USD

Preparing tissue for enzymatic dissociation—whether for flow cytometry, single-cell sequencing, or primary cell culture—often begins with the same tedious step: holding a razor blade or scissors in one hand, stabilizing the tissue with forceps in the other, and cutting it into small pieces one cut at a time.

After processing multiple samples, repetitive cutting can quickly become tiring. More importantly, manually minced tissue is often uneven, with large fragments left behind. These larger pieces may digest more slowly or incompletely, contributing to inconsistent single-cell release and greater sample-to-sample variability.

The BenchArt™ Multi-Blade Tissue Chopper offers a faster and more consistent approach. The standard blade holder accommodates eight parallel No. 9 single-edge razor blades at a nominal spacing of 2 mm. Each controlled downward pass makes eight evenly spaced cuts simultaneously. By repositioning or rotating the tissue between passes, users can rapidly produce more uniformly sized fragments while substantially reducing repetitive hand movements.

The standard 2 mm spacing is well suited to many tissue-dissociation workflows that call for tissue fragments in the approximate 2–4 mm range. Depending on the tissue type, sample size, and desired fragment size, a task that may require several minutes with a single blade can often be completed in a series of controlled passes within seconds.

Interchangeable blade holders and matching cleaning combs are also available separately, supporting four to eight blades with nominal spacing options ranging from 4 mm to 2 mm. This allows the chopper to be configured for different tissues and processing requirements.

The included cleaning comb helps remove tissue fragments trapped between the blades. A protective cover provides convenient storage for the blade assembly and cleaning comb when the tool is not in use. Blade replacement is straightforward: remove the locating pin, detach the blade holder, replace the blades, reinstall the holder, and fully reinsert the pin.

The printed components are made from PETG and can be cleaned with water, PBS, mild detergent, or 70% ethanol. The product is not autoclavable.

For Research Use Only (RUO). Not intended for clinical, diagnostic, or surgical use.

Default Blade Capacity: 8 blades

Default Blade Spacing: 2 mm nominal blade-to-blade spacing

Compatible Blades: No. 9 single-edge razor blades

Package Content: Handle, 8-blade holder, locating pin, protective cover, and matching cleaning comb. Razor blades are not included.

Optional Accessories: Interchangeable blade holders and matching cleaning combs supporting 4–8 blades with nominal spacing options from 4 mm to 2 mm

Material: PETG

Autoclavable: No

Sterility: Supplied non-sterile

Before each use, inspect the handle, blade holder, locating pin, cleaning comb, and protective cover for cracks, deformation, or other damage. Confirm that the blade holder and locating pin are securely installed.

To install or replace the blades, place the chopper on a stable surface, carefully remove the locating pin, and detach the blade holder from the handle. Remove the used blades with forceps or another suitable tool. Insert compatible No. 9 single-edge razor blades into the designated slots with all cutting edges aligned in the same direction. Reattach the blade holder and fully insert the locating pin before use. Do not touch the cutting edges directly.

Place the tissue on a stable, suitable cutting surface or in an appropriate sample vessel. Hold the chopper securely by the handle and press the blades vertically through the tissue using a controlled downward motion. Lift the blades completely before repositioning or rotating the tissue. Repeat from one or more directions until the desired fragment size is obtained. Do not twist, drag, or apply excessive sideways force to the blades.

After cutting, use the supplied cleaning comb to remove tissue fragments from between the blades while keeping fingers away from all cutting edges.

When processing consecutive samples with the same blades, and when permitted by the experimental protocol, remove visible tissue with water or PBS and clean the blades and blade holder with 70% ethanol or isopropyl alcohol. Before processing live cells or alcohol-sensitive samples, remove residual alcohol by rinsing with sterile water or PBS as appropriate for the workflow. Use fresh blades or a validated decontamination procedure whenever sterility, cross-contamination, nucleic acid carryover, or sample identity is a concern.

After use, clean the components, allow them to dry completely, and install the protective cover before storage. Do not autoclave or expose the PETG components to excessive heat.

Razor blades are extremely sharp and may cause serious cuts or puncture injuries. Handle, install, remove, and dispose of blades with appropriate forceps or tools. Cut-resistant gloves are recommended when handling exposed blades; standard disposable laboratory gloves do not provide reliable cut protection.

Keep fingers, hands, and other objects away from the cutting path during use. Never remove tissue from between the blades with your fingers; use the supplied cleaning comb or suitable forceps.

Always cut on a stable surface using controlled vertical pressure. Do not twist, pry, or apply excessive sideways force, as this may damage the blade holder or cause a blade to bend, break, or become dislodged.

Do not use the product if any component is cracked, warped, loose, or damaged. Confirm that the locating pin is fully inserted before every use. Install the protective cover whenever the chopper is not in use.

Dispose of used or damaged blades in an approved sharps container in accordance with applicable institutional and local regulations. Keep the product and replacement blades out of reach of children and unauthorized users.